广东工业大学学报 ›› 2011, Vol. 28 ›› Issue (4): 74-78.

• 综合研究 • 上一篇    下一篇

复方中草药在超声波药物耦合剂中的抗菌效果

  

  1. 广东工业大学 轻工化工学院,广东 广州 510090
  • 出版日期:2011-12-25 发布日期:2011-12-25
  • 作者简介:袁国正(1943-),男,副研究员,主要研究方向为高分子化学、医用材料及植物药应用.
  • 基金资助:

    广东省教育部科技部企业特派员行动计划专项项目(2009B090600138)

Antimicrophyte Effect of the Compound Plant Medicine in -Ultrasonically-Enhanced Transdermall Drug Gel

  1. Faculty of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510090,China
  • Online:2011-12-25 Published:2011-12-25

摘要: 研究超声波耦合剂导入药物中草药的抗菌效果.导入药物为含当归、何首乌、忍冬藤、芦荟和薄荷醇的复方制剂.试验结果表明,复方中草药由于抗菌叠加效应,各种单味药相互之间存在互补性,抗菌效果明显提高.大肠杆菌和金黄色葡萄球菌的杀灭率都大于99%,红色毛癣菌平均达到8527%,而对白色念珠菌杀菌率只有6211%,对黑曲霉菌的杀菌率低至109%.采用琼脂扩散法试验体外细胞毒性反应为1级,符合生物相容性国家技术要求.

关键词: 抗菌作用;中草药;当归;忍冬;何首乌;芦荟;超声波耦合剂

Abstract: The antimicrophyte effect of the compound plant medicine in ultrasonicallyenhanced transdermal drug gel is studied. The transdermal drug contained the compound with Chinese Angelica, Fleeceflower Root, Lonicera japonica Thunb, Aloe and Lmenthol. Compounding so many plant medicines resulted in a significantly increased antimicrophyte effect, which might be due to accumulative effect plus analternation action.The experimental results show that the rate of sterilizing both Escherchia coli and Staphlococus aureus allare is more than 99 percent, and the rate of sterilizing Trichophyto rubrurn is 85.27 percent, but the rate of sterilizing candida aibicans is only 62.11 percent. The grade of outbody cytotoxicity test ranks the first, and the test result is in accordance with the official specification of China.  

Key words: antimicrophyte effect; plant medicine; lonicera japonica thunb; polygonum multiflorum thumb; aloe bar badensis miller; ultrasound transmission gel angelica sinensis(oliv)

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