Abstract: A resistivity measuring system of thermoelectric material was designed with the LabVIEW as software and the circuit of control and data acquisition as hardware, in order to overcome the problem of low resistivity measurement accuracy. The measurement system has the characteristics of high measuring accuracy, wide measurement range, friendly interface and rich display information. It has an ability to finish manual measurement or automatic measurement. At the same time, it can change the direction of current with controllable frequency in order to improve the measurement accuracy. Experiments show that the relative error within -0.25%~+0.25%. It is a valuable measurement system for property measurement of thermoelectric material.