心脏补片的生物力学研究评述

doi:10.3969/j.issn.1007-7162.2012.02.006

摘要/Abstract

摘要： 细胞移植是心肌组织工程中治疗心肌梗死的一种潜在的治疗方法.心脏补片不仅是种子细胞的载体，还可抑制心脏的膨胀扩张，以促进种子细胞对梗死心肌组织的修复再生.心脏补片的研制已经成为基础与临床医学、材料科学和生物力学等的交叉热点.本文评述了心脏补片的生物力学研究现状，并就本领域今后值得关注的问题进行展望.
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关键词: 心肌组织工程；心脏补片；生物力学；生物降解；优化设计

Abstract: Cell transplantation is a potential treatment for myocardial infarction in myocardial tissue engineering. The heart patch is not only the carrier of the seed cells, but it can also inhibit the expansion of the heart to facilitate the myocardial repair and regeneration. The development of the heart patch has become an interdisciplinary focus of basic and clinical medicine, materials science and biomechanics. It reviews the study of the heart patch in biomechanics, and proposes several points deserving further investigation in this field.

Key words: myocardial tissue engineering; heart patch; biomechanics; biodegradation; optimal design

张吉桥. 心脏补片的生物力学研究评述[J]. 广东工业大学学报, 2012, 29(2): 33-37.

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